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Development of Functionalized Derivatives for the Application in a Novel Bioorthogonal Ligation Strategy and for the Design of IHF Mimicking Peptides

Printausgabe
EUR 57,60

E-Book
EUR 40,32

Development of Functionalized Derivatives for the Application in a Novel Bioorthogonal Ligation Strategy and for the Design of IHF Mimicking Peptides

Cornelia Hannah Panse (Autor)

Vorschau

Inhaltsverzeichnis, PDF (390 KB)
Leseprobe, PDF (3,2 MB)

ISBN-13 (Printausgabe) 9783736990852
ISBN-13 (E-Book) 9783736980853
Sprache Englisch
Seitenanzahl 280
Umschlagkaschierung glänzend
Auflage 1. Aufl.
Erscheinungsort Göttingen
Promotionsort Göttingen
Erscheinungsdatum 21.08.2015
Allgemeine Einordnung Dissertation
Fachbereiche Chemie
Organische Chemie
Beschreibung

Proteins are involved in countless cellular transformations. Owing to their diverse and significant role in biological systems, biologically relevant macromolecules have gained attention as target structures in order to elucidate their functions and to design novel bioactive materials with respect to medical applications. [l,2l Especially, site selective functionalizations of proteins allow the examination of the special and temporal localization, dynamics and function of biologically active samples in a cellular environment and more importantly even at the molecular level. l31 However, in many cases selectively functionalized proteins are difficult to access by applying recombinant techniques as these are limited to genetically encoded amino acids and site directed modifications are often impossible to control.l11