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Function of microRNAs in skeletal muscle cell differentiation (Tienda española)
Swanhild Meyer (Autor)Previo
Lectura de prueba, PDF (360 KB)
Indice, PDF (74 KB)
| ISBN-13 (Impresion) | 9783736993068 |
| ISBN-13 (E-Book) | 9783736983069 |
| Idioma | Inglés |
| Numero de paginas | 92 |
| Laminacion de la cubierta | mate |
| Edicion | 1. Aufl. |
| Lugar de publicacion | Göttingen |
| Lugar de la disertacion | TU München |
| Fecha de publicacion | 27.07.2016 |
| Clasificacion simple | Tesis doctoral |
| Area |
Bioquímica, biología molecular, tecnología genética
|
| Palabras claves | micro-RNA, skeletalmuscle, myoblast, target prediction, microarray, real-time qPCR, normalization, geneexpression, cell differentiation |
Descripcion
Skeletal muscle cell differentiation is exogenously regulated by cytokines and growth factors and it is post-transcriptionally regulated by microRNAs (miRNAs). This study presents miRNA and gene expression data of differentiating skeletal muscles with or without concomitant TNF-alpha or IGF1 exposure to elucidate the function of miRNAs. Results indicate specific miRNA-target relations during skeletal muscle differentiation and show that miRNAs mediate the effect of TNF-alpha.
