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Function of microRNAs in skeletal muscle cell differentiation (Tienda española)
Swanhild Meyer (Autor)Previo
Lectura de prueba, PDF (360 KB)
Indice, PDF (74 KB)
Skeletal muscle cell differentiation is exogenously regulated by cytokines and growth factors and it is post-transcriptionally regulated by microRNAs (miRNAs). This study presents miRNA and gene expression data of differentiating skeletal muscles with or without concomitant TNF-alpha or IGF1 exposure to elucidate the function of miRNAs. Results indicate specific miRNA-target relations during skeletal muscle differentiation and show that miRNAs mediate the effect of TNF-alpha.
| ISBN-13 (Impresion) | 9783736993068 |
| ISBN-13 (E-Book) | 9783736983069 |
| Idioma | Inglés |
| Numero de paginas | 92 |
| Laminacion de la cubierta | mate |
| Edicion | 1. Aufl. |
| Lugar de publicacion | Göttingen |
| Lugar de la disertacion | TU München |
| Fecha de publicacion | 27.07.2016 |
| Clasificacion simple | Tesis doctoral |
| Area |
Bioquímica, biología molecular, tecnología genética
|
| Palabras claves | micro-RNA, skeletalmuscle, myoblast, target prediction, microarray, real-time qPCR, normalization, geneexpression, cell differentiation |
