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Function of microRNAs in skeletal muscle cell differentiation (English shop)
Swanhild Meyer (Author)Preview
Extract, PDF (360 KB)
Table of Contents, PDF (74 KB)
Skeletal muscle cell differentiation is exogenously regulated by cytokines and growth factors and it is post-transcriptionally regulated by microRNAs (miRNAs). This study presents miRNA and gene expression data of differentiating skeletal muscles with or without concomitant TNF-alpha or IGF1 exposure to elucidate the function of miRNAs. Results indicate specific miRNA-target relations during skeletal muscle differentiation and show that miRNAs mediate the effect of TNF-alpha.
| ISBN-13 (Hard Copy) | 9783736993068 |
| ISBN-13 (eBook) | 9783736983069 |
| Language | English |
| Page Number | 92 |
| Lamination of Cover | matt |
| Edition | 1. Aufl. |
| Publication Place | Göttingen |
| Place of Dissertation | TU München |
| Publication Date | 2016-07-27 |
| General Categorization | Dissertation |
| Departments |
Biochemistry, molecular biology, gene technology
|
| Keywords | micro-RNA, skeletalmuscle, myoblast, target prediction, microarray, real-time qPCR, normalization, geneexpression, cell differentiation |
