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Editorial Cuvillier

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Biological and Chemical Investigations of Indonesian Marine-Derived Fungi and their Secondary Metabolites

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EUR 33,65 EUR 0,00

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Biological and Chemical Investigations of Indonesian Marine-Derived Fungi and their Secondary Metabolites (Tienda española)

Kustiariyah Tarman (Autor)

Previo

Indice, Datei (160 KB)
Lectura de prueba, Datei (220 KB)

ISBN-10 (Impresion) 3869557133
ISBN-13 (Impresion) 9783869557137
ISBN-13 (E-Book) 9783736937130
Idioma Inglés
Numero de paginas 198
Edicion 1 Auflage
Volumen 0
Lugar de publicacion Göttingen
Lugar de la disertacion Universität Greifswald
Fecha de publicacion 04.04.2011
Clasificacion simple Tesis doctoral
Area Bioquímica, biología molecular, tecnología genética
Descripcion

In the search for bioactive compounds, 32 fungal strains were isolated from Indonesian marine habitats. Ethyl acetate extracts of their culture broth were tested for cytotoxic activity against a urinary bladder carcinoma cell line and for antifungal and antibacterial activities against fish and human pathogenic bacteria as well as against plant and human pathogenic fungi. Bioassay-guided fractionation led to the isolation of bioactive compounds. Altogether 14 compounds were isolated and further elucidated. The compounds were obtained from the ethyl acetate and dichloromethane extracts of six fungal strains. They included 9 polyketides, 2 terpenes, 1 alkaloid and 2 till now undefined structures.