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Influence of heterogeneous bubbly flows on mixing and mass transfer performance in stirred tanks for mammalian cell cultivation

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EUR 54.90

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Influence of heterogeneous bubbly flows on mixing and mass transfer performance in stirred tanks for mammalian cell cultivation (Volume 5) (English shop)

A study in transparent 3 L and 12 000 L reactors

Annika Rosseburg (Author)

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ISBN-13 (Hard Copy) 9783736971080
ISBN-13 (eBook) 9783736961081
Language English
Page Number 152
Lamination of Cover matt
Edition 1.
Book Series Berichte aus dem Institut für Mehrphasenströmungen
Volume 5
Publication Place Göttingen
Place of Dissertation Hamburg
Publication Date 2019-11-12
General Categorization Dissertation
Departments Mechanical and process engineering
Keywords Aerated stirred tank reactor, scale up, mass transfer, mixing time, flow structures, heterogeneity, bubbly flow, scale, laboratory, reactors, determine, industrial, influence, mass, aerated, processes, stirred, mixing, viscosity, impeller, radial, axial, compartments, baffles, lead, complexity, described, average, reactor, structures, Belüfteter Rührkesselreaktor, vergrößern, Mischzeit, Skala, Labor, Reaktoren Stoffaustausch,Heterogenität, Blasenströmung Strömungsstrukturen, bestimmen, Einfluss, Masse, belüftet, Prozesse, gerührt, Mischen, Viskosität, Laufrad, radial, axial, Fächer, Komplexität
Description

Aerated stirred tank reactors are widely used in chemical and pharmaceutical industry in which mass transport and mixing time are among the most important parameters. Despite their importance, the prediction of theses parameters is still challenging due to large differences of the hydrodynamic inhomogeneities between lab scale and industrial scale. This thesis focuses on the measurement of these inhomogeneities and their influence on the important process parameters. In order to determine the differences to industrial processes, a transparent stirred tank reactor on industrial scale has been erected at the Hamburg University of Technology.