Zur bakteriellen Oberflächenpräsentation kombinatorischer Peptidbibliotheken und deren Anwendung auf Fragestellungen der Immunologie, Molekularbiologie und der Molekualren Medizin (English shop)

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This dissertation investigates bacterial surface display of combinatorial peptide and protein libraries for analyzing molecular interactions. Using an Intimin-based display system, peptides are presented on the surface of Escherichia coli and screened for specific binding properties. The research focuses on identifying and mapping antibody epitopes and generating and selecting novel peptides and microproteins with defined binding characteristics. The study explores applications of these techniques in immunology, molecular biology, biotechnology, and molecular medicine.