Cuvillier Verlag

Publications, Dissertations, Habilitations & Brochures.
International Specialist Publishing House for Science and Economy

Cuvillier Verlag

De En Es
Bioinspired Organometallic Analogues of Iron-Sites in Metalloproteins

Hard Copy
EUR 39.10

E-book
EUR 27.00

Bioinspired Organometallic Analogues of Iron-Sites in Metalloproteins (English shop)

Steffen Meyer (Author)

Preview

Table of Contents, PDF (140 KB)
Extract, PDF (270 KB)

Metalloproteins with iron-sites are essential for almost all living organisms and responsible for a large number of biological redox reactions. To uncover the mechanisms of enzymes and cofactors, bioinorganic chemistry aims to provide low-molecular weight analogues. In this dissertation, the iron-sites of [2Fe–2S] proteins, [NiFe] hydrogenases and mononuclear oxygenases served as models for bioinspired analogues coordinated by N-heterocyclic carbene (NHC) ligands. Although abiological, NHC ligands have been shown to be capable of stabilizing otherwise labile inorganic intermediates which are crucial for mechanistic understanding. Using this approach, the isolation of the first organometallic oxoiron(IV) complex, mimicking the oxygenase motif, was achieved. Studies on the structural and magnetic characteristics, substrate reactivity, and the decomposition pathway are provided.

ISBN-13 (Hard Copy) 9783954049202
ISBN-13 (eBook) 9783736949201
Language English
Page Number 184
Lamination of Cover matt
Edition 1. Aufl.
Publication Place Göttingen
Place of Dissertation Göttingen
Publication Date 2015-01-29
General Categorization Dissertation
Departments Chemistry
Keywords Bioinorganic Chemistry, Organometallic Chemistry, Iron, Metalloproteins, N-Heterocyclic Carbene, Oxoiron (IV)