Flexible, Konformationell Präorganisierte Strukturelemente - Konformationsinduktion und Anionenrezeptoren (Volume 1) (English shop)

Preview

Table of Contents, Datei (51 KB)
Extract, Datei (91 KB)

The work carried out and successfully completed in the second part of this thesis shows that the concept of an anion receptor which spans a cavity by means of flexible, preorganised side chains is viable and can, building on the work carried out by HETTCHE, be transferred to larger systems. Unfortunately, access to the direct analogues of HETTCHE’s receptors, the mellitic acid trisimide receptors, was barred owing to the susceptibility of the mellitic acid trisimide group to reduction on the one hand and the susceptibility of the urea function to acylation on the other. One conceivable way of nevertheless obtaining such receptors consists in selecting other binding groups that tolerate strongly acylating conditions. However, the synthesis of a receptor with different binding groups would limit comparability with the preceding work. Nevertheless, further work is desirable in order to synthesise C3-symmetric receptors that complex larger C3-symmetric anions such as nitrates and carbonates. Receptors whose binding groups span an even larger space than the ureas investigated here appear, according to the findings obtained in this work, to be beset with problems. In the case of anions that are too small to fill the space spanned by the binding groups, complexes with a stoichiometry higher than 1:1 are to be expected.