|Book Series (74)||
|Biochemistry, molecular biology, gene technology||105|
|Domestic and nutritional science||39|
|Environmental research, ecology and landscape conservation||125|
|Place of Dissertation||Braunschweig|
|Keywords||Pyrrolizidine alkaloids, herbal medicine, honey, Lappula squarrosa, HPLC-ESI-MS/MS, food safety, Ghana, Germany|
Plant and animal-derived products have been part of human diet since time immemorial. However, recent reports of the presence of toxic pyrrolizidine alkaloids (PAs) in some of these products have raised concerns of their potential hepatotoxic, pneumotoxic, genotoxic, mutagenic and carcinogenic effects in both humans and livestock. This study therefore aims at quantifying and profiling PAs in honey, herbal products and the tissues of Lappula squarrosa, using LC-ESI-MS/MS, in order to ascertain their potential health risk.